Can I Take My Vitamins With Plavix and Low Dose Aspirin

What is the difference between aspirin and Plavix (clopidogrel)?

  • Aspirin and Plavix (clopidogrel bisulfate) are drugs used to forbid blood clots.
  • Aspirin and Plavix vest to dissimilar drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).
  • Aspirin as well is used to reduce fever, and to treat pain and inflammation in the trunk.
  • Side effects of Plavix and aspirin that are similar include:
  • Abdominal pain/burning sensation/cramping, and liver damage or failure.
  • Side effects of Plavix that are unlike from aspirin include:
    • Diarrhea
    • Rash
    • Itching
    • Headache
    • Chest pain
    • Musculus aches
    • Dizziness
    • Severe bleeding
    • Allergic reactions
    • Pancreatitis
  • Side effects of aspirin that are different from Plavix include:
    • Ringing in the ears (tinnitus)
    • Gastrointestinal ulcers or haemorrhage
    • Nausea
    • Gastritis
  • Aspirin and Plavix are more effective when taken together, but information technology increases the adventure of bleeding.
  • Make names for aspirin include Bayer and Ecotrin. Aspirin is available over-the-counter (OTC) and in generic form.

What is aspirin? What is Plavix (clopidogrel)? Are they the aforementioned?

What is aspirin? How does it work?

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used to care for fever, pain, and inflammation in the body. It also prevents blood clots and is used to prevent heart attack and stroke. Other NSAIDs include ibuprofen (Aleve, Motrin), indomethacin (Indocin), and nabumetone (Relafen).

NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins, and reducing levels of inflammation, pain, and fever. Inhibition of prostaglandins also reduces the role of platelets and the power of blood to jell. Aspirin inhibits the role of platelets in a style different from other NSAIDs and its antithrombotic furnishings terminal longer than other NSAIDs.

What is Plavix? How does information technology work?

Plavix (clopidogrel bisulfate) is an anti-platelet drug used to foreclose blood clots. Plavix is used to reduce the risk of centre attacks and strokes, particularly in people with a recent history of stroke or heart set on, and those with peripheral vascular disease.

Plavix works by bounden to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets. Information technology belongs to a course of drugs called P2Y12 inhibitors. Other P2Y12 inhibitors include ticagrelor (Brilinta) and prasugrel (Effient). Clopidogrel is similar to ticlopidine (Ticlid) in chemic structure and in the way information technology works.

What are the side effects of aspirin vs. Plavix?

Aspirin side effects

Most people benefit from aspirin and other NSAIDs with few side effects. However, serious side effects tin occur and generally tend to exist dose-related. Therefore, it is appropriate to use the everyman constructive dose to minimize side effects.

The about common side effects of aspirin involve the gastrointestinal system and ringing in the ears.

Gastrointestinal side furnishings of aspirin

  • Ulcers
  • Abdominal burning
  • Hurting
  • Cramping
  • Nausea
  • Gastritis
  • Serious gastrointestinal bleeding
  • Liver toxicity

Sometimes, ulceration and bleeding tin occur without whatever abdominal pain. Black tarry stools, weakness, and dizziness upon standing may exist the but signs of internal bleeding.

The daily dose of aspirin should be reduced if you take ringing in the ears (tinnitus).

Other side effects of aspirin include:

  • Rash
  • Kidney impairment
  • Vertigo
  • Dizziness

Other side effects and adverse reactions of aspirin

  • People with peptic ulcers or poor kidney function should avoid taking aspirin since it can aggravate both atmospheric condition.
  • Aspirin may exacerbate asthma.
  • Aspirin can raise the blood uric acid level and is avoided in patients with hyperuricemia and gout.
  • Children and teenagers should avert aspirin for symptoms of the flu or chickenpox because of the associated risk of Reye's syndrome, a serious affliction of the liver and nervous organization that tin can lead to coma and death.
  • Aspirin can increase the outcome of medicines used to treat diabetes mellitus, resulting in abnormally depression claret sugars if blood saccharide levels are not monitored.

NSAIDs should be discontinued prior to elective surgery because of a mild tendency to interfere with blood clotting. Aspirin, because of its prolonged effect on platelets, is best discontinued at least ten to fourteen days in accelerate of the procedure.

Plavix side effects

The tolerability of clopidogrel is similar to that of aspirin. Common side effects of clopidogrel are:

  • Diarrhea
  • Rash
  • Itching
  • Abdominal Pain
  • Headache
  • Breast Hurting
  • Muscle aches
  • Dizziness

Side effects of Plavix that are more serious include:

  • Severe bleeding
  • Allergic reactions
  • Pancreatitis
  • Liver failure

Ticlopidine (Ticlid) is an antiplatelet medication quite similar to clopidogrel. It has been associated with a severe reduction in white blood jail cell count in between 0.8% and 1% of persons. The risk of this dangerous side consequence with clopidogrel is almost 0.04%, much less than with ticlopidine but twice that of aspirin.

Clopidogrel rarely causes a condition called thrombotic thrombocytopenic purpura (TTP) in one out of every 250,000 people. TTP is a serious status in which blood clots form throughout the body. Blood platelets, which participate in clotting, are consumed, and the result can be bleeding considering enough platelets are no longer left to permit blood to jell usually. For comparison, the related drug, ticlopidine (Ticlid), causes TTP 17-50 times more often than clopidogrel.

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What is the dosage of aspirin vs. Plavix?

Aspirin dosage

  • You lot should take aspirin with nutrient. Doses range from 50 mg to 6000 mg daily depending on the use.
  • Usual doses for mild to moderate pain are 350 or 650 mg every 4 hours or 500 mg every half dozen hours.
  • Doses for rheumatoid arthritis include 500 mg every 4-half dozen hours; 650 mg every 4 hours; 1000 mg every iv-6 hours; 1950 mg twice daily.
  • Heart attacks are prevented with 75, 81, 162, or 325 mg daily.
  • 160 to 325 mg of non-enteric coated aspirin should be chewed immediately when experiencing symptoms of a eye attack.
  • The dose for preventing another stroke is 75 to 100 mg daily.

Plavix dosage

  • Clopidogrel bisulfate commonly is taken in one case daily.
  • Plavix can be taken with or without nutrient.
  • Clopidogrel is activated by enzymes in the liver to its active grade. People who take reduced action of liver enzymes that activate clopidogrel due to liver affliction may not respond adequately to clopidogrel. Alternative treatments should be used for these patients.
  • The recommended dose for treating unstable angina or center set on is 300 mg initially followed past 75 mg daily in combination with 75-325 mg of aspirin.
  • Peripheral arterial disease or recent stroke is treated with 75 mg daily.

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What Happens Afterward a Stroke? Signs, Symptoms, Types See Slideshow

What are the drug interactions of aspirin and Plavix?

Aspirin drug interactions

Aspirin is associated with several suspected or likely interactions that bear on the action of other drugs. Examples of the most mutual of the suspected interactions include:

  • NSAIDs may increase the blood levels of lithium (Eskalith, Lithobid) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may atomic number 82 to lithium toxicity.
  • Aspirin may reduce the blood pressure level lowering furnishings of blood pressure medications. This may occur because prostaglandins accept a function in the regulation of blood force per unit area.
  • When aspirin is used in combination with methotrexate (Rheumatrex, Trexall) or aminoglycoside antibiotics (for example, gentamicin) the blood levels of the methotrexate or aminoglycoside may increment, presumably because their elimination from the body is reduced. This may pb to more methotrexate or aminoglycoside-related side effects.

Individuals taking oral blood thinners or anticoagulants, for example, warfarin, (Coumadin) should avoid aspirin because aspirin also thins the blood, and excessive blood thinning may atomic number 82 to serious haemorrhage.

Plavix drug interactions

  • The combination of clopidogrel with nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin increase the risk of tum and abdominal bleeding. Other NSAIDs include ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Aleve), diclofenac (Voltaren), etodolac (Lodine), nabumetone (Relafen), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis, Oruvail), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), and mefenamic acid (Ponstel) may increase the risk of tum and intestinal bleeding.
  • Combining clopidogrel with warfarin (Coumadin) or other drugs that crusade bleeding increases the take chances of bleeding.
  • Clopidogrel is converted to its agile form by enzymes in the liver. Drugs that reduce the action of these enzymes, for instance, omeprazole (Prilosec, Zegerid) or esomeprazole (Nexium) may reduce the activity of clopidogrel and should non be used with clopidogrel. Other drugs that too may react with clopidogrel in a similar fashion include fluoxetine (Prozac, Sarafem), cimetidine (Tagamet), fluconazole (Diflucan), ketoconazole (Nizoral, Extina, Xolegel, Kuric), voriconazole (Vfend), ethaverine (Ethatab, Ethavex), felbamate (Felbatol), and fluvoxamine (Luvox).

Are aspirin or Plavix safe to accept if I'thousand pregnant or breastfeeding?

Aspirin safety

  • Aspirin is generally avoided during pregnancy because information technology may adversely effect the fetus. Notwithstanding, low aspirin doses accept been safely used for the prevention of complications of pregnancy.
  • Aspirin is excreted into chest milk and may crusade adverse effects in the babe.

Plavix condom

  • There are no adequate studies of clopidogrel in significant women.
  • Studies in rats have shown that clopidogrel appears in breast milk; however, it is not known whether it also appears in human breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing clopidogrel to nursing mothers.

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Medically Reviewed on 12/7/2021

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